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    You are at:Home » ALL RECIPES » Classic Southern Meatloaf with Sweet & Tangy Glaze
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    Classic Southern Meatloaf with Sweet & Tangy Glaze

    Master ChefBy Master Chef12/28/2025No Comments2 Mins Read
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    Classic Southern Meatloaf with Sweet & Tangy Glaze

    A Tender, Juicy Comfort Food Favorite
    Nothing says Southern comfort food like a classic homemade meatloaf fresh from the oven. This Southern Meatloaf recipe is moist, flavorful, and topped with a rich sweet-and-tangy ketchup glaze that caramelizes beautifully as it bakes. Made with simple pantry ingredients and seasoned just right, this old-fashioned meatloaf is perfect for family dinners, Sunday suppers, or cozy weeknight meals.
    Serve it with creamy mashed potatoes, green beans, or buttered corn for a hearty, satisfying meal that feels like home.

    Ingredients:

    Meatloaf
    2 lbs ground beef (80/20 for best flavor and juiciness)
    1 cup breadcrumbs or crushed crackers
    2 large eggs
    ½ cup milk
    1 small onion, finely diced
    2 cloves garlic, minced
    1 tsp salt
    ½ tsp black pepper
    1 tsp garlic powder
    1 tsp onion powder
    1 tsp paprika
    1 tbsp Worcestershire sauce
    Sweet & Tangy Glaze
    ½ cup ketchup
    2 tbsp brown sugar
    1 tbsp mustard

    Instructions:

    Preheat oven to 350°F (175°C). Grease a loaf pan or line a baking sheet with parchment paper.
    In a large bowl, gently combine ground beef, breadcrumbs, eggs, milk, onion, garlic, seasonings, and Worcestershire sauce. Mix just until combined do not overmix.
    Shape mixture into a loaf and place in the prepared pan or on the baking sheet.
    In a small bowl, mix ketchup, brown sugar, and mustard.
    Spread half of the glaze evenly over the meatloaf.
    Bake for 45 minutes. Remove from oven and spread remaining glaze on top.
    Return to oven and bake an additional 15–20 minutes, until fully cooked and caramelized.
    Let rest for 10 minutes before slicing. Serve warm and enjoy.

    Why You’ll Love This Southern Meatloaf:

    Comfort food classic the whole family loves
    Moist and juicy thanks to milk, eggs, and 80/20 beef
    Easy weeknight dinner with simple ingredients
    Great for leftovers & meal prep
    Perfect for Southern-style dinners and holiday meals

    Southern meatloaf, classic southern meatloaf recipe, homemade meatloaf, old fashioned meatloaf, easy meatloaf recipe, comfort food dinner, meatloaf with ketchup glaze, family dinner recipes, traditional meatloaf

    Classic Southern meatloaf made with juicy ground beef and topped with a sweet, tangy ketchup glaze. An easy comfort food dinner perfect for family meals and cozy weeknights.

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